Cthrc1 kda

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August undefined, 2024

WebOct 11, 2024 · Background Metastasis is the major cause of morbidity and mortality in patients with epithelial ovarian cancer (EOC), however the mechanisms that underline this process are poorly understood. Collagen triple helix repeat containing-1 (CTHRC1) is a 28-kDa secreted protein reported to be involved in vascular remodeling, bone formation … WebCTHRC1 is highly expressed multiple human cancers, including pancreatic cancer where it plays a significant role in the progression and metastasis of the disease by regulating migration and adhesion of tumors cells. CTHRC1 overexpression can also be used as an independent prognostic marker in gastric cancer.

Anti-CTHRC1 antibody (ab85739) Abcam

Web~Two bands of 25-30 kDa (SDS-PAGE) Purity: ≥90% (SDS-PAGE) Endotoxin Content: 0.01EU/μg purified protein (LAL test). Concentration: 0.1mg/ml after reconstitution. ... Collagen triple helix repeat containing-1 (CTHRC1) is a 30kDa glycosylated secretory protein containing a short collagen-like motif contributing to vascular remodeling by ... WebMar 1, 2005 · Collagen triple helix repeat containing 1 (CTHRC1) is a 28-kDa secreted glycoprotein containing a short collagen motif with 12 Gly-X-Y repeats, and it is highly conserved from lower chordates to ... danny phantom reality trip

Regulation of CTHRC1 expression. A and B. Western …

WebMay 19, 2014 · The gene that coded for collagen triple helix repeat containing 1 (CTHRC1), located at chromosome 8q22.3, was overexpressed in HCC compared with normal or liver cirrhosis tissues and identified as a new HCC-related gene. ... Fig. 1D shows that the 26-kDa CTHRC1 protein was expressed in membrane fractions of the HepG2 … WebThe recombinant human CTHRC1 consists of 224 amino acids and has a predicted molecular mass of 24.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh CTHRC1 is approximately … WebCollagen triple helix repeat containing 1: Protein class i. Disease related genes Human disease related genes: Predicted location i. Intracellular,Secreted ... 26.2 kDa Yes: 0: CTHRC1-202 ENSP00000416045 ENST00000415886: E7EVQ5 [Direct mapping] Collagen triple helix repeat-containing protein 1 . Show all. birthday lemon cake recipe

CTHRC1 promotes M2-like macrophage recruitment and

WebCollagen triple helix repeat containing-1 (CTHRC1) is a 28-kDa secreted protein, reported to be involved in vascular remodeling, bone formation and morphogenesis [19]. In addition to functioning in the context of arterial injury, recent studies have reported CTHRC1 acts as a prognostic factor. Furthermore, it promotes tumor WebFeb 9, 2012 · Collagen Triple Helix Repeat Containing-1 (CTHRC1) and Nuclear factor (erythroid-derived 2)-like 3 ... expression level in colorectal tumours when compared with normal tissues [9-12]. CTHRC1 is a 30 kDa secreted protein that has the ability to inhibit collagen matrix synthesis. birthday lesson planWebApr 15, 2002 · Hepatocellular carcinoma (HCC) Malignant behaviors microRNA-155-5p (miR-155-5p) Collagen triple helix repeat containing 1 (CTHRC1) GSK-3β-involved Wnt/β-catenin signaling; ... Osteosarcoma microRNA-338-3p Activator of 90 kDa heat shock protein ATPase homolog 1 Tumor suppressor Translational repression; 82. danny phantom respect thread

"WebCTHRC1 is specifically expressed in vascular calcifications of carotid artery lesions and may contribute to vascular remodeling of injured arteries (Pyagay et al., 2005 [PubMed 15618538]).[supplied by OMIM] " - Cthrc1 kda

Cthrc1 kda

Expression analysis of the novel gene collagen triple helix repeat ...

WebMay 13, 2024 · CTHRC1 is highly expressed in patients with primary CRC and hepatic metastasis of CRC and predicts a poor prognosis. To … WebFor the independent antibodies validation the evaluation is based on comparison of the staining of two (or more) independent antibodies directed towards independent epitopes on the protein. For all cases except the siRNA validation, an image representative of the antibody staining pattern is shown.

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WebAug 12, 2024 · CTHRC1 expresses mainly in adventitial fibroblasts and neointimal smooth muscle cells of balloon-injured vessels and promotes cell migration and tissue repair in response to injury. CTHRC1 plays a ... WebOct 11, 2024 · Collagen triple helix repeat containing-1 (CTHRC1) is a 28-kDa secreted protein reported to be involved in vascular remodeling, bone formation and morphogenesis. This study aimed to investigate the role of CTHRC1 in promoting the metastasis of EOC and to elucidate the underlying molecular mechanisms.

WebCTHRC1 gene deletion leads to fatty liver (steatosis) formation in mice while others exhibited inactivation of the CTHRC1 gene also results in low bone mass. Description. CTHRC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 234 amino acids (31-243 a.a) and having a molecular mass of 25.3kDa. ... WebCTHRC1 (Collagen triple helix repeat-containing protein 1) is a 28-30 kDa, secreted glycoprotein that bears similarity to the C1q/TNF alpha -related family of proteins. It is expressed by disparate cell types, …

WebOct 26, 2024 · The function of collagen triple helix repeat containing 1 (CTHRC1) as an oncogene has been reported in a growing number of publications. ... Highly conserved from lower chordates to mammals, the CTHRC1 protein was identified as a 30 kDa secreted protein and was first verified to be a differentially expressed gene in balloon-injured rat …

WebCTHRC1, a 28-kDa secreted ECM protein, could promote cell migration via limiting collagen matrix deposition [16]. ... (TAMs) is associated with tumor progression and poor prognosis in endometrial ...

WebAll lanes : Anti-CTHRC1 antibody (ab264410) at 1/1000 dilution Lane 1 : UACC-62 whole cell lysate Lane 2 : MALME-3M whole cell lysate Lane 3 : SR whole cell lysate Lane 4 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate Lysates/proteins at 50 µg per lane. Developed using the ECL technique. Predicted band … birthday letter formatWebCTHRC1 is expressed in calcified atherosclerotic plaque and chondrocyte-like cells, in the hypothalamus, pituitary gland and remodeling tissues. Aberrant expression of CTHRC1 is present in human solid cancers and likely to be associated with … danny phantom sayonara fanfictionWeb25.3 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. ... There are no reviews for CTHRC1 Recombinant Protein (NBP2-52008). By submitting a review you will ... danny phantom reality trip ninjaWebAll lanes : Anti-CTHRC1 antibody (ab264411) at 1/1000 dilution Lane 1 : UACC-62 whole cell lysate Lane 2 : MALME-62 whole cell lysate Lane 3 : SR whole cell lysate Lane 4 : NIH/3T3 (mouse embryo fibroblast cell line) whole cell lysate Lysates/proteins at 50 µg per lane. Developed using the ECL technique. Predicted band size: 26 kDa Exposure time: … birthday letterWebCTHRC1 protein expression summary. Single band larger than predicted size in kDa (+20%) but partly supported by experimental and/or bioinformatic data. birthday letter ideasWebCTHRC1 was immunoprecipitated from 0.35 mg SK-MEL-28 (Human malignant melanoma) whole cell lysate with ab256458 at 1/30 dilution (2ug in 0.35mg lysates). Western blot was performed on the immunoprecipitate using ab256458 at 1/1000 dilution. VeriBlot for IP Detection Reagent (HRP) was used at 1/5000 dilution. birthday letter for boyfriend long distanceWebMay 13, 2024 · CTHRC1 is highly expressed in patients with primary CRC and hepatic metastasis of CRC and predicts a poor prognosis. To identify the potential metastasis-associated genes in primary CRC, we first ... birthday letter design ideas